Oxigênio em alto fluxo para cefaleia em salvas
Um guia completo para usar oxigênio em alto fluxo para abortar crises de cefaleia em salvas: como funciona, como usá-lo bem e como conseguir acesso.
Oxygen: the gold-standard legal treatment
High-flow oxygen is the safest legal treatment to abort cluster headache attacks. In controlled trials, about four out of five responders stop an attack within 15 minutes of starting, without side effects or rebound headaches.[1] Many patients report stopping attacks with oxygen in less than 10 minutes. It is recognized as the first-line acute treatment by the European Academy of Neurology.[2] Vaped DMT can end an attack even faster where it is accessible; see our DMT guide.
Oxygen is unusual among medical treatments: how quickly it works, and whether it works at all, depends heavily on how you use it. Finding the equipment, setting and technique that work for you can be a real challenge. This guide exists to help you with that.
I and others who have been here long enough have learned that when someone says they tried oxygen and it didn't work […] it is very, very likely that their use of oxygen was far from optimized, and it might very well be worth trying again. […] Many, many folks who thought O2 didn't work for them have found that it works fine when done 'right.'
— CHfather, longtime ClusterBusters forum moderator
At a glance: the best oxygen setups and techniques
In every case, you will need a cylinder of pressurized, pure oxygen. From there, two equipment setups are known to work well, each paired with its own breathing technique:
| Setup | Pros and cons | Breathing technique |
|---|---|---|
| Demand valve setup | A demand valve releases oxygen on demand (as fast as you can breathe), making it the quickest way to abort an attack with oxygen. It can be harder to get prescribed and more expensive than the alternative. | Hyperventilate on pure oxygen: full inhale, full exhale, repeat as fast as possible. |
| Non-rebreather mask with a sufficiently high-flow regulator (explained just below). | Works well for most people, given the right regulator (25 LPM or more is recommended) and a good breathing technique. Often easier to get prescribed than a demand valve. With enough flow, aborts attacks about as quickly as a demand valve; with lower flow, the bag-refill pause between breaths can make it somewhat slower to act. | Forceful deep breathing: empty your lungs, then take a deep breath of pure oxygen. Repeat as fast as your reservoir bag can keep up. Only pause between breaths if the bag hasn't refilled. |
A regulator is the part that attaches to the oxygen cylinder and controls how much oxygen comes out, measured in liters per minute (LPM).

The two setups and breathing techniques that work
Demand valve setup
A demand valve delivers oxygen only when you inhale, and it can keep up with very fast breathing.
The breathing technique. With a demand valve, you hyperventilate on pure oxygen: inhale fully, exhale fully, and repeat as fast as you can. This is widely considered the fastest and easiest way to abort a cluster attack with oxygen. In a randomized crossover trial, demand valves roughly halved the need for rescue medication compared with a standard mask, and most patients preferred them.[3]
Demand valve technique: inhale fully, exhale fully, repeat as fast as you can.
Demonstration video of the hyperventilation technique with a demand valve.
The setup. A demand valve usually requires a pressure regulator. This is different from a standard flow regulator (also called LPM regulator) used with non-rebreather masks. And demand valves themselves are expensive, meaning they can be harder to get through a prescription. For this reason, some patients skip the prescription route entirely and source their oxygen and equipment from welding suppliers. See our welding oxygen guide.
Reservoir bag setup: ClusterO2 kit or non-rebreather mask
A ClusterO2 kit or standard non-rebreather mask uses a reservoir bag. Oxygen flows into the bag continuously, and you breathe from the bag through a mask or a mouthpiece. This setup works well for most people, and it is often easier to get prescribed than a demand valve. However, the bag holds a limited stock of pure oxygen: if you breathe faster than the regulator can refill it, the bag empties and you have to wait for it to catch up. That's why it's important to get a regulator that is as high LPM as possible.
The breathing technique. Empty your lungs as forcefully as you can, then take a deep inhale, filling your lungs with pure oxygen. The pace depends on your flow. If the reservoir bag stays full between breaths, breathe as fast as you're capable of, at the same pace as with a demand valve. If the bag starts running low, pause briefly between breaths to give it time to refill.
Deep breathing technique: exhale completely, inhale pure oxygen, repeat as soon as the bag refills.
Demonstration video of the deep breathing technique with a ClusterO2 kit.
The setup. The most important choice is the regulator. At least 25 LPM is strongly recommended. Regulators delivering 40 LPM are often available and inexpensive, and at that flow the setup can abort attacks about as quickly as a demand valve (at the cost of using more oxygen per attack). The right flow varies between people; you'll dial it in as you refine your technique. See Aborting an attack with oxygen for how.
What to avoid
To abort an attack, the gas you breathe needs to be pure oxygen, undiluted. That means three things to avoid:
- Oxygen concentrators. They produce oxygen at lower purity and at a flow rate too low for cluster aborts. The source gas must come from a pure-oxygen cylinder.
- Nasal cannulas, and masks with open side vents. They let room air mix with the oxygen you inhale. If your prescribed non-rebreather mask has side vents, you can block them. See the Equipment chapter.
- Masks without a reservoir bag. Without a bag to hold a stock of pure oxygen between breaths, the mask cannot deliver enough oxygen on the inhale to completely fill your lungs.
References
- ↩ Cohen AS, Burns B, Goadsby PJ (2009). High-flow oxygen for treatment of cluster headache: a randomized trial. JAMA, 302(22), 2451–2457. Link
- ↩ May A, Evers S, Goadsby PJ, Leone M, Manzoni GC, Pascual J, et al. (2023). European Academy of Neurology guidelines on the treatment of cluster headache. European Journal of Neurology, 30(10), 2955–2979. doi:10.1111/ene.15956
- ↩ Petersen AS, Barloese MCJ, Lund NLT, Jensen RH (2017). Oxygen therapy for cluster headache. A mask comparison trial. A single-blinded, placebo-controlled, crossover study. Cephalalgia, 37(3), 214–224. doi:10.1177/0333102416637817
Esta página foi útil para você?
Capítulos
- 1. Aborting an attack with oxygenHow to use oxygen during a cluster attack. Done well, it ends the pain within minutes for most patients. When it doesn't, the culprit is usually equipment, flow, or breathing technique, all of which can be fixed.
- 2. EquipmentWhat each piece of the setup does, how to choose it, and what "good" looks like.
- 3. Getting access to oxygenHow to get home oxygen prescribed, delivered, and covered, with escalation tactics and fallbacks for every place the process can stall.
- 4. Welding oxygen: a practical alternativeWhen you can't get medical oxygen: what welding oxygen is, why it's safe, and how to source it.
- 5. Frequently asked questionsShort answers to the questions patients most often ask about cluster headache oxygen therapy. Deeper coverage of each topic lives on the relevant sub-page; links are included throughout.
Isenção de Responsabilidade
As informações deste site são fornecidas apenas para fins educacionais e de redução de danos. Elas não constituem aconselhamento médico e não devem substituir a consulta com um profissional de saúde qualificado. Consulte nossa página Aviso Legal para mais detalhes.